Salt of pentamidine, pharmaceutical composition, pharmaceutical liposome formulation, pharmaceutical formulation, a process for treating pneumonia caused by Pneumocystis carinue,Process for prophylaxis against pneumonia caused by Pneumocystis carinue,The process for prophylaxis against an initial episode of pneumonia caused by Pneumocystis carinue and composition of pharmacologically useful

摘要

Salts of pentamidine, formulations containing such salts and the use of such salts for treatment or prophylaxis of pneumocystis carinii. Pentamidine gluconate and lactate has been discovered and found to have high water solubility while providing potentially less toxic alternatives to pentamidine isethionate, especially for aerosolized administration to patients suffering from acquired immunodeficiency syndrome, AIDS, or AIDS related complex, ARC.