HUMAN HYBRIDOMAS CELL LINES PRODUCING MONOCLONAL ANTIBODIES CAPABLE OF DISTINGUISHING NEOPLASTIC CELLS FROM NORMAL CELLS,ANTIBODIES PRODUCED BY THEM AND METHOD FOR DETERMINING THE PRESENCE OF A NEOPLASM BY USING SAID ANTIBODIES

摘要

Cells of human cervical tissue suspected of being neoplasmic, such as cervical carcinoma, prostate tumour, lung cancer, etc. are combined in a buffered aq. test medium with mono-clonal anti-bodies capable of distinguishing between normal and neoplasmic cervical cells. The anti-bodies are tagged with a marker capable of giving a detectable signal. Union of the anti-bodies with the human cell tissue is detected by presence of the signal in the test medium. The monoclonal anti-bodies are obtd. from a human hybridoma CLNH5 or CLNH11, or hybridoma derived from these.