首页> 外国专利> use of derivatives of fosfatidil carnitine for the preparation of pharmaceutical compositions having activity in the treatment of human diseases associated with neuronal damage.

use of derivatives of fosfatidil carnitine for the preparation of pharmaceutical compositions having activity in the treatment of human diseases associated with neuronal damage.

机译:地非他定肉碱衍生物在制备具有治疗与神经元损伤有关的人类疾病中具有活性的药物组合物中的用途。

摘要

We describe the use of phospholipidic carnitine derivatives of general formula CHEM in their racemic or optically active form, wherein R1 and R2, equal or different, are radicals of linear or branched, saturated or mono-or poly-unsaturated, aliphatic acids with 1 to 20 C for the preparation of pharmaceutical compositions having an activity as reproductive agent of the nerve fibers in the therapy of human pathologies associated with neuronal damages, more particularly in the therapy of peripheral neuropathies, of cerebrovascular diseases, of cerebral level traumas and of chronic neurodegenerative diseases.
机译:我们描述了外消旋或旋光活性形式的通式的磷脂肉碱衍生物的用途,其中R 1和R 2相等或不同,是直链或支链,饱和或单或多不饱和脂肪族酸与1-20℃用于制备药物组合物,该药物组合物具有作为神经纤维的再生剂的活性,用于治疗与神经元损伤有关的人体病理学,更特别是用于治疗周围神经病,脑血管疾病,脑水平创伤和神经损伤。慢性神经退行性疾病。

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