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RECOMBINANT HISTIDINE-RICH PROTEIN (37KD ANTIGEN) OF PLASMODIUM FALCIPARUM, ITS PREPARATION AND USE
RECOMBINANT HISTIDINE-RICH PROTEIN (37KD ANTIGEN) OF PLASMODIUM FALCIPARUM, ITS PREPARATION AND USE
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机译:恶性疟原虫重组富组氨酸蛋白(37KD抗原)及其制备和用途
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摘要
A gene which codes for a histidine/alanine-rich protein has been isolated by screening two different Plasmodium falciparum cDNA gene banks with antiserum against a 41 kD protein and by cross-hybridisation with the insert DNA of a clone obtained therewith. The protein protects aotus monkeys from infection with P. falciparum and is thus a suitable component of a malaria vaccine.
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