MEASUREMENT OF PGE2 (PROSTAGLANDIN E2) LEVELS IN PATIENTS WITH CHRONIC INFLAMMATORY BOWEL DISEASE

摘要

The present invention relates to a process (1) for evaluating disease activity in patients with chronic inflammatory bowel diseases (IBD), termed ulcerative colitis (UC) and Crohn's colitis (CC), respectively, and (2) for predicting (a) the outcome of medical treatment in severe, active diseases, where acute or subacute surgery may be an alternative, in addition to (b) the risk of relapse in symptom-free patients, who wish to stop relapse preventing medication. Furthermore, the invention relates to a kit to be used in the process described. The test kit includes dialysis bags for oral intake and/or rectal insertion, in addition to essential and specific test substances for the performance of radioimmunological determination of PGE2 in the contents of the dialysis bags.