in vitro carried out on peripheral leucocytes of the patient which determines either one or both of the anti-idiotypic T cell responses or the anti-activated indicator cell response."/> Monitoring of efficacy of vaccination
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Monitoring of efficacy of vaccination

机译:监测疫苗接种效果

摘要

The invention relates to an assay for determining the efficacy of vaccination of a patient in need thereof against an autoimmune disease and to means for carrying out such assay.;Vaccinations are carried out by means of activated treated T cells, or membranes of these or fragments of such membranes. The assay according to the invention is in the form of a skin test or in the form of a proliferative assay in vitro carried out on peripheral leucocytes of the patient which determines either one or both of the anti-idiotypic T cell responses or the anti-activated indicator cell response.
机译:本发明涉及一种用于确定需要其的患者对自身免疫疾病的疫苗接种的功效的测定法,并且涉及用于进行这种测定的方法。疫苗接种是通过活化的经处理的T细胞或其膜或这些片段的膜来进行的。这样的膜。根据本发明的测定法是对患者的外周血白细胞进行的皮肤试验或体外增生测定法,其确定一个或两个。抗独特型T细胞应答或抗活化指示细胞应答。

著录项

  • 公开/公告号EP0291046A1

    专利类型

  • 公开/公告日1988-11-17

    原文格式PDF

  • 申请/专利权人 YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED;

    申请/专利号EP19880107612

  • 发明设计人 COHEN IRUN ROBERT;

    申请日1988-05-11

  • 分类号G01N33/80;G01N33/564;

  • 国家 EP

  • 入库时间 2022-08-22 06:35:22

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