L-ascorbic acid which comprises (a) forming a substantially anhydrous slurry of 2-keto-l-gulonic acid and at least one lipophilic surfactant having a low hydrophilic:lipophilic balance of from about 4.3 to about 10.2 in a supporting organic layer which optionally contains a co-solvent and (b) reacting said slurry with a substantially anhydrous hydrogen chloride gas acid catalyst to convert said 2-keto-l-gulonic acid to L-ascorbic acid."/>
公开/公告号EP0324261A1
专利类型
公开/公告日1989-07-19
原文格式PDF
申请/专利权人 PFIZER INC.;
申请/专利号EP19880312161
发明设计人 LOZANOV MERRILL;
申请日1988-12-22
分类号C07D307/62;
国家 EP
入库时间 2022-08-22 06:34:03