The bone density of post-menopausal women is increased by employing a calendar-oriented regimen of estrogen, progesterone and calcium wherein the estrogen is ingested for days 1 to 25 of the calendar month, progesterone for days 16 to 25 and calcium for day 26 to the end of the calendar month. Such a regimen may be dispensed from a calendar- oriented pill dispenser having numerical indicia identifying each pill-containing enclosure with a given calendar date.
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