Composition and method for treatment and metaphylaxis of urate and mixed urate lithiasis

摘要

A combination and method for treatment and metaphylaxis of urate and mixed urate lithiasis is disclosed. The active component of the invention is a non-ionogenic surfactant of the formula R-COO(CH.sub.2 CH. sub.2 O). sub.n H, wherein R is linolic acid, linolenic acid, or oleinic acid, and n is a number from 18 to 40. The active component forms a complex water- soluble compound with uric acis, thereby dissolving urate calculi and eliminating uric acid from the urine. The invention exhibits rapid and reliable therapeutic effect, without side effects, and without reliance on maintenance of urine pH.