The present invention provides a compound having the formula ##STR1## wherein Y is biotin or iminobiotin, X is CH.sub.2, P is psoralen or a psoralen derivative, r is an integer equal to or greater than 2 and s is an integer equal to or greater than 1.PPThe invention also provides a method for preparing a biotinylated psoralen or a biotinylated psoralen derivative.PPFurther provided are methods for detecting, purifying, and isolating nucleic acids, and methods for delivering an iminobiotinylated psoralen to a cell.
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