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NEW POLYACETYLENE-BASED COMPOUND AND 5-LIPOXYGENASE INHIBITOR CONTAINING POLYACETYLENE-BASED COMPOUNDS AS ACTIVE INGREDIENT
NEW POLYACETYLENE-BASED COMPOUND AND 5-LIPOXYGENASE INHIBITOR CONTAINING POLYACETYLENE-BASED COMPOUNDS AS ACTIVE INGREDIENT
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机译:新的基于聚苯乙烯的化合物和含有基于聚苯乙烯的化合物的5-脂氧合酶抑制剂作为活性成分
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摘要
NEW MATERIAL:9,10-Epoxy-1,16-heptadecadien-4,6-diyn-3-one expressed by the formula. USE:A 5-lipoxygenase inhibitor. PREPARATION:For example, a carrot is extracted with a solvent such as hexane, diethyl ether, acetone or methanol and the solvent is removed from the resultant extract to provide a residue, which is subjected to column chromatography or high performance liquid chromatography using a porous polymer, silica gel, polyamide, cellulose, etc., as a carrier and hexane, diethyl ether, acetone, methanol, water, etc., as a solvent. The raw material component is purified with the layer chromatography or high performance liquid chromatography. The raw material component is oxidized using an oxidizing agent such as an active manganese (IV) oxide or chromium (VI) oxide.
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