SUBSTITUTED 3-(N-HETEROCYCLIC)-2, 6-DIAMINOPIRIDINE AND -N-OXIDE, PRODUCTION THEREOF AND ANALGESTIC ANTI-EPILEPSY DRUG CONTAINING THE SAME AND PRODUCTION THEREOF

摘要

Compounds of the general formula: IMAGE I wherein the radicals R1 and R2 are the same or different and represent hydrogen or C1-C6-alkyl, the radicals R3 and R4 are the same or different and represent hydrogen, C1-C6-alkyl, hydroxy, C1-C6-alkoxy, C2-C6-alkanoyloxy, halogen or C2-C6-alkanoyl, X is oxygen, sulphur or the group -NR5 and R5 is hydrogen, C1-C6-alkyl, C2-C6-alkanoyl or benzoyl, m and n in each case may represent the integers 1, 2 or 3 and the phenyl radical A is unsubsituted or is substituted by halogen, nitro, C1-C6-alkyl, trifluoromethyl, C3-C7-cycloalkyl, hydroxy, C1-C6-alkoxy, C2-C6-alkanoyloxy, amino, C1-C6-alkylamino, di-C1-C6-alkylamino, C2-C6-alkanoylamino, CN, carboxy, C1-C6-alkoxycarbonyl, phenyl, C1-C6-alkylphenyl or trifluoromethylphenyl, their pyridine-N-oxides and physiologically acceptable salts thereof, processes for their preparation and medicines containing such compounds as active ingredients.