D-HOMO-4,17-ANDROSTADIENE-3-ONE, MANUFACTURE AND MEDICINE HAVING ANTI-ANDROGENIC ACTIVITY AND FAT PRODUCTION INHIBITING ACTIVITY

摘要

D-Homo-4,17-androstadien-3-one is a pharmacologically effective compound having antiandrogenic activity upon topical application. The compound can be prepared from D-homo-5,17-androstadien-3 beta -ol by oxidation with simultaneous isomerization of the 5(6)-double bond.