1,2,4-DITHIAZOLIDINE-3,5-DIONE COMPOUND, ITS PREPARATION, AND GERMICIDE CONTAINING SAID COMPOUND AS ACTIVE COMPONENT

摘要

NEW MATERIAL:The compound of formulaI(R is H or lower alkyl; X is phenyl substituted with cyano, nitro, lower alkyl, CF3, alkoxyl, phenoxy or benzyloxy, pyridinyl, or naphthyl). EXAMPLE:4-(3,5-Dioxo-1,2,4-dithiazolidin-4-ylmethyl)pyridine. USE:Germicide. It is useful as an agent for controlling plant blight and an antifungal agent for medical use, having strong antifungal activity against fungi in man and animals. It has no phytotoxicity to agricultural crop, low toxocity to man, animals, fish and environmental animals, and high safety. PROCESS:The compound of formulaIcan be obtained by recting a thiocabamate compound of formula II (R1 is lower alkyl) with equimolar amount of chlorocarbonylsulfenyl chloride of formula III if necessary in the presence of dehydrochlorinating agent.