PURPOSE:To provide a dissolving aid for enhancing the solubility of a hardly soluble substance to water, obtained by containing bisdesmosides. CONSTITUTION:As a dissolving aid for enhancing the solubility of a hardly soluble substance to water in a preparation process of medicine, bisdesmoside compound is contained as effective component. This bisdesmoside compound has a genine part comprising a terpenoid skeletal or a steroid skeletal and is one containing a so called saponin. This dissolving aid is used in an amount of about 0.02-10mg per 1ml of water.
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