Glycoprotein, DNA sequence coding for the same, replicable cloning auxiliary agent, pharmaceutical preparation comprising the glycoprotein and the process for the purification of the glycoprotein

摘要

Highly active glycoprotein plasminogen activators which exhibit a stringent requirement for the presence of a fibrin cofactor, and which readily catalyze the lysis of plasma clots. The plasminogen activator can be produced by host microorganisms or eukaryotic cells which have been transformed by expression vectors having an inserted DNA sequence encoding the glycoprotein.