Use of a blodpladeaktiveringsfaktorantagonist in combination with monoclonal or polyclonal antibodies in a pharmaceutical composition for the treatment of endotoxic shock in mammals

摘要

The invention is a method of treating endotoxic shock in a mammal which comprises administering to the mammal a therapeutically effective amount of an antagonist to Platelet Activating Factor in combination with a therapeutically effective amount of one or more monoclonal or polyclonal antibodies directed towards either Tumor Necrosis Factor alpha , Interieukin-1 beta , Gamma Interferon, or bacterial cell wall lipopolysaccharides.