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CONTROLLED RELEASE TABLET HAVING CORE CONTAINING WATER-SWELLABLE POLYMER AND COATING OF SEMIPERMEABLE POLYMERIC DIFFUSION FILM
CONTROLLED RELEASE TABLET HAVING CORE CONTAINING WATER-SWELLABLE POLYMER AND COATING OF SEMIPERMEABLE POLYMERIC DIFFUSION FILM
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机译:具有包含水溶胀性聚合物的芯和半渗透性聚合物扩散膜涂层的可控制的释放片剂
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摘要
A controlled release tablet comprising I) a core, containing as essential components a) at least one water-soluble pharmaceutically active substance which is dispersed in a water-insoluble, non-digestible polymeric excipient, and b) a water-insoluble polymeric substance, which is swellable under the influence of water, and II) a coating consisting essentially of an elastic, water-insoluble and semipermeable diffusion film of a polymer, is presented, which shows a release pattern for the active substance(s) in a programmed rate of approximately zero order.
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