TOPICAL PHARMACEUTICAL COMPOSITIONS CONTAINING DICLOFENAC AND A SKIN PERMEABILITY ENHANCING CYCLIC AMIDE

摘要

There are disclosed novel pharmaceutical compositions which comprise diclofenac or a salt thereof, a penetration agent such as 1-n-dodecylazacycloheptan-2-one or dimethyllauroylamide and, as vehicle, a mineral oil. These compositions have excellent skin penetration properties and can therefore be used in transdermal therapeutic systems (TTS) as drug reservoir.