14,15-DIHYDRO-14,15-METHYLENE (AND HALO SUBSTITUTED METHYLENE) MILBEMYCIN DERIVATIVES AND BIOCIDAL COMPOSITIONS

摘要

Novel compounds of formula IMAGE (I) in which A is a IMAGE group wherein R1 is hydrogen or an OH-protecting group, and R11 is hydrogen, an OH-protecting group, or an alkyl, cycloalkyl or acyl group, R2 is methyl, ethyl, isopropyl, sec.-butyl or a -C(CH3)=CH-E group wherein E is methyl, ethyl or isopropyl, R3 and R4 together represent a bond between the two carbon atoms to which they are bonded, or together represent a -C(X')(Z')- group wherein X' and Z' each represents, independently of the other, hydrogen or halogen, and X and Z each represents, independently of the other, hydrogen or halogen, the preparation of the novel compounds and the use thereof for controlling parasites of productive livestock and for controlling harmful insects.