METHOD OF DETECTING PREGNANCY IN ITS BLASTOGENETIC PERIOD

• 1. 一种检测妊娠期糖尿病遗传易感性的试剂盒 [P] . 中国专利： CN110229876A . 2019-09-13
• 2. 一种基于人工智能辅助妊娠期糖尿病遗传风险预测的方法 [P] . 中国专利： CN110246577B . 2021.04.30
• 3. PREGNANCY TIME PERIOD FORECASTING DEVICE, PREGNANCY TIME PERIOD FORECASTING METHOD, AND PREGNANCY TIME PERIOD FORECASTING PROGRAM [P] . 世界知识产权组织专利： WO2018101462A1 . 2018-06-07

  机译： 妊娠期预测装置，妊娠期预测方法和妊娠期预测程序

• 4. PREGNANCY PERIOD PREDICTION DEVICE AND PREGNANCY PERIOD PREDICTION METHOD AND PREGNANCY PERIOD PREDICTION PROGRAM [P] . 日本专利： JP2018092331A . 2018-06-14

  机译： 妊娠期预测装置和妊娠期预测方法及妊娠期预测程序

• 5. METHOD FOR DIAGNOSING PREGNANCY PROCESS EXCEEDING THE PREGNANCY PERIOD [P] . UA61643A . 2003-11-17

  机译： 诊断超出怀孕期的怀孕过程的方法

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• 2. Incidental Serous Tubal Intraepithelial Carcinoma Detected by a Surgery for Ectopic Pregnancy [J] . Takuro Yamamoto, Koki Shimura, Takuya Sugahara, 妇产科期刊（英文） . 2020,第005期
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• 5. Pregnancy and multiple sclerosis: Disease modifying therapies in the peripartum period. [D] . Berman, Sari. 2016
• 6. Reduction in blood platelet size with increase in circulating numbers in the postoperative period and a comparison of the glass bead and rotating bulb methods for detecting changes in function [O] . J. B. Enticknap, T. S. Lansley, Thelma Davis 1970
• 7. Table 3: Discriminative power of the ReproQ based on statistical power (significance perspective) and the ability to detect 1.0 and 0.5 MID difference (relevance perspective) for all ReproQ outcomes during pregnancy (npu = 42), childbirth and postnatal period (npu = 55). (A) The mean best-practices is the pooled average of the 10 best performing units. [O] . -1

• 1. Novel Method of Detecting Pregnancy Using Microwaves [J] . Anil Lonappan . 电磁分析与应用期刊（英文） . 2012,第8期
• 2. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 3. 猫微卫星DNA标记遗传检测方法的优化及对实验用虎皮猫群体遗传结构分析 [C] . YI Shuai ,衣帅 ,任文陟 . 2013‘第十一届中国北方实验动物科技年会 . 2013
• 4. 实验用鱼遗传检测方法的建立——对斑马鱼、剑尾鱼遗传检测方法的研究 [A] . 魏杰 . 2009