PROCESS FOR THE ISOLATION AND PURIFICATION OF A NEW LYMPHOCINE SUPPRESSING PLATING ACTIVATION

摘要

PCT No. PCT/FR87/00164 Sec. 371 Date Mar. 1, 1988 Sec. 102(e) Date Mar. 1, 1988 PCT Filed May 19, 1987 PCT Pub. No. WO87/07303 PCT Pub. Date Dec. 3, 1987.New lymphokine and its isolation and purification process. Said lymphokine is comprised of a factor obtained from T cells stimulated by concanavaline A or by an antigen capable of inhibiting the IgE-dependent platelet citotoxicity with respect to young larvae of S. Mansoni, of strongly reducing the chemiluminescence of blood platelets in a reaction IgE-anti-IgE, which is a correlate of the anti-parasite cytotoxicity, and of inhibiting the platelet activation in non-IgE dependent intolerences. Application as suppressor agent for suppressing platelet activation and as immunomodulator medicament of allergies.