PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOUNDS WITH THROMBOLITIC ACTIVITY CONTAINING AN UROKINASE AND PRO-UROKINASE SYNERGIC MIXTURE

摘要

Case 118-6968 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS The thrombolytic effect of the plasminogen activator pro-urokinase is improved synergistically by the co-administration of urokinase. The two components may be administered sequentially or simultaneously, and if simultaneously, either separately or as a mixture. Preferably an initial bolus injection of urokinase is followed by an infusion of pro-urokinase.