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PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS WITH IMMUNOSUPPRESSIVE ACTIVITY, CONTAINING 4-IMINO-1,3-DIAZABICYCLO- (3.1.0) -HEXANO-2-ONA
PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS WITH IMMUNOSUPPRESSIVE ACTIVITY, CONTAINING 4-IMINO-1,3-DIAZABICYCLO- (3.1.0) -HEXANO-2-ONA
The present invention relates to the use of 4-imino-1,3-diazabicyclo[3.1.0]hexan-2-one (imexon) as an immunosuppressive agent. Imexon selectively suppresses beta -lymphocyte activation and can be employed for the treatment of B-cell or plasma-cell leukaemia and neoplasms. Imexon is used in the treatment of those disorders in which polyclonal B-cell proliferation is of pathophysiological, symptomatic or clinical relevance such as, for example, for autoimmune diseases.
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