4-IMINO-1,3-DIAZOBICYCLO(3.1.0)HEXAN-2-ONE,PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

摘要

4-Imino-1,3-diazabicyclo[3.1.0]-hexan-2-one of one or more of the tautomeric formulas IMAGE or a physiologically compatible salt thereof exhibits cancerostatic and immuno-stimulant activity. It is produced by cyclized 1-carboxamido-2-cyanoaziridine in an anhydrous polar organic solvent in the presence of a catalytic amount of an alkali.