Process for the preparation of an oral anti-bacterial composition comprising an anti-bacterial agent and an aminoguanidine

摘要

An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which substantially prevents staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanides such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride are typical examples of antibacterial agents. The antistain additive is an aminoguanidine free base or water soluble salt thereof compatible with the bis-biguanide or quaternary ammonium salt.