首页> 外国专利> polipeptidici derivatives with high iron content and highly soluble acts to therapy martial preparation procedure and their pharmaceutical forms

polipeptidici derivatives with high iron content and highly soluble acts to therapy martial preparation procedure and their pharmaceutical forms

机译:高铁含量和高可溶性的脂肽衍生物对武术制备过程及其药物形式的作用

摘要

Polypeptide derivatives containing 0.1 to 45% by weight of iron, which are highly soluble at neutral/basic pH and insoluble at acid pH, obtained by a) hydrolysis of succinylated proteins containing iron (FeSP), or b) interaction of succinylated peptides with iron salts (II or III). Said derivatives are very good iron carriers after by oral administration in mammals and show an extremely good tolerability.
机译:含0.1%至45%重量的铁的多肽衍生物,其在中性/碱性pH下高度可溶而在酸性pH下不溶,可通过以下方法获得:a)水解含铁的琥珀酰化蛋白质(FeSP),或b)琥珀酰化肽与铁的相互作用盐(II或III)。所述衍生物在哺乳动物中口服给药后是非常好的铁载体,并且显示出极好的耐受性。

著录项

  • 公开/公告号IT1222912B

    专利类型

  • 公开/公告日1990-09-12

    原文格式PDF

  • 申请/专利权人 ITALFARMACO S.P.A.;

    申请/专利号IT19870022276

  • 发明设计人 SPORTOLETTI GIANCARLO;CREMONESI PIETRO;

    申请日1987-10-14

  • 分类号A61K;

  • 国家 IT

  • 入库时间 2022-08-22 06:17:09

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号