2-AMINO-4-SUBSTITUTED-5-HYDROXYPYRIMIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF PULMONARY ASTHMATIC, ALLERGIC, INFLAMMATORY OF GASTROINTESTINAL DISEASES

摘要

HYDROXY AND ALKOXY PYRIMIDINESAbstract2-Amino-4-substituted-5-(hydroxy or alkoxy)-pyrimidines, which may be 6-substituted, and deriva-tives thereof are inhibitors of leukotriene synthesisand are therefore useful for the treatment of pul-monary, inflammatory, allergic and cardiovasculardiseases. The compounds are also cytoprotective andtherefore useful in the treatment of peptic ulcers.