SYNTHESIS OF 2,2'-BIS- -OXAZOLINE

摘要

CASE 2979 "NEW SYNTHESIS OF 2,2'-BIS-.DELTA.2-OXAZOLINE" The present invention relates to a new method of synthesis of 2,2'-bis.DELTA.2-oxazoline, which consists of three steps: in the first step, N,N'-bis-(2-hydroxyethyl)-oxamide (I) is reacted with hydrogen chloride and a nitrile of formula RCN in which R = H, alkyl, aryl, arylalkyl, alkylaryl, in order to yield the corresponding N,N'-bis-(2-iminoacyloxyethyl)oxamide.2HCl (II). In the second step, the compound (II) is pyrolysed in order to yield N,N'-bis-(2-chloroethyl)oxamide (III) which in the third step generates, by means of the treatment with a base, the desired product 2,2'-bis-.DELTA.2-oxazoline.