首页>
外国专利>
Affinity markers for hormonal steroid receptors, their use in hormonoradio therapy and as imaging agents of hormone-dependent cancers
Affinity markers for hormonal steroid receptors, their use in hormonoradio therapy and as imaging agents of hormone-dependent cancers
展开▼
机译:激素类固醇受体的亲和标记物,在激素放射治疗中的使用以及作为激素依赖性癌症的成像剂
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention relates to affinity markers consisting of a specific and irreversible ligand for steroid hormone receptors, characterised in that they consist of an oestrogen complex consisting of an oestradiol derivative complexed by an organometallic compound fixed in position 17 alpha of oestradiol, an oestrogen complex whose PKR+, which measures the constant of equilibrium between the 17 beta -alcohol and the 17-carbenium form of the said complex, is negative. The present invention also relates to the application of these affinity markers as imaging agents for hormone-dependent cancers and as medication for hormonal radiotherapy when these affinity markers comprise suitably chosen radioactive isotopes.
展开▼