Bactobolin as a prophylactic or therapeutic agent for autoimmune diseases, and as an immuno-suppressive agent

摘要

A known antibiotic substance, bactobolin is now found to be useful to treat an autoimmune disease, as demonstrated by the treatment of experimental allergic encephalomyelitis (EAE) with bactobolin. Bactobolin is also effective to suppress lymphocyte proliferative response to specific antigen or mitogen. Generally, bactobolin is now found to be effective as an immunosuppressive agent.