CATALYTIC HYBRIDIZATION SYSTEMS FOR THE DETECTION OF NUCLEIC ACID SEQUENCES BASED ON THEIR ACTIVITY AS COFACTORS IN CATALYTIC REACTIONS IN WHICH A COMPLEMENTARY LABELED NUCLEIC ACID PROBE IS CLEAVED

摘要

A kind of detection nucleic acid (DNA or RNA) target sequence, wherein this sequence is reacted as the catalysis of co-factor, wherein complementary, labeled nucleic acid probe is cleaved such that target sequence is released complete and can recycle the channel that reaction is formed repeatedly, to provide signal amplification.