1-(AMINOALKYL)-ALPHA,ALPHA-DIARYL PYRROLIDINE-PIPERIDINE-AND HOMO PIPERIDINE-ACETAMIDES AND ACETONITRILES AND PREPARING PROCESS THEREOF

摘要

Acetamides and acetonitriles of formula (I) and their salts are prepd. by reacting a cpd. of formula (II) with a cpd. of formula halo-(CH2)x-NR1R2. In the formulas, n=0-2; Ar1 and Ar2 each = 2-, 3- or 4-pyrido, phenyl or phenyl substd. by C1-3 alkyl, alkoxy, halogen or CF3; Y= aminocarbonyl or CN; x= 2-5; R= H or lower alkyl; R1 and R2 each = H, lower alkyl, phenyl, phenyl substd. by halogen, lower alkyl or alkoxy, or R1 and R2 together with the N may form pyrrolidino, piperidino, piperazino or morpholino. (I) are used for correcting and preventing cardiac arrhythmia.