PROCESS FOR THE PRODUCTION OF NORMAL BUTYRIC ACID BY FERMENTATION FROM A SUGAR SUBSTRATE IN THE PRESENCE OF AT LEAST ONE STRAIN OF THE SPECIES CLOSTRIDIUM

摘要

A process is described for producing, in a reaction zone, a mixture of organic acids or corresponding salts containing a major part of n-butyric acid or its corresponding salt, by fermentation of a reaction medium. initial composition containing a sweet substrate, in the presence of at least one strain belonging to the Clostridium species. According to the invention, the following steps are carried out: a) the strain is fed to the substrate at a concentration between 1 and 80 g of substrate per liter of initial reaction medium, b) the substrate concentration is allowed to decrease by at least 20% of its initial value and up to a value such that it is between 0 and 30 g of substrate per liter of initial reaction medium, c) the strain is fed to said substrate at a flow rate of between 0.01 and 25 g per liter of initial reaction medium and per hour and such that the residual concentration of said substrate during the duration of power supply entation is at most equal to 80 g / l of initial reaction medium, and d) the mixture of acids or salts thus produced is recovered. / P