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IN VIVO RECOMBINING METHOD OF DNA SEQUENCES HAVING BASE MESAPPARITIONS
IN VIVO RECOMBINING METHOD OF DNA SEQUENCES HAVING BASE MESAPPARITIONS
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机译:具有碱基介导作用的DNA序列的体内重组方法
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摘要
In vivo recombination process for partially homologous DNA sequences having up to 30% base mismatches. Said sequences are contacted in cells or in an organism whose enzymatic system for repairing mismatches is deficient or has been temporarily inactivated by saturation for a period of time sufficient to achieve recombination between said DNA sequences or any other mutant which increases intergenetic recombination.
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