High performance anion-exchange chromatographic packing composition consisting of low porosity synthetic resin gel particle substrate coated with liquid water-soluble aminated resin

摘要

An anion-exchange chromatographic packing composition which comprises:PPa substrate which consists essentially of particles having cation-exchanging sites at least on their available surfaces, the particles being of a diameter of between about 1 to about 75 microns; andPPa liquid coating which consists essentially of a hydrophilic, water soluble, film forming resin having anion-exchanging sites which attract available cation-exchanging sites of the substrate, wherein the liquid coating is retained by electrostatic bonds on the available surfaces of the substrate particles. The invention further includes a chromatographic column and process using the described packing composition.