Two-dimensional method for spectral editing of NMR signals produced by metabolites containing coupled spins

摘要

An NMR method for acquiring the volume localized, in vivo proton spectra of spin-spin coupled metabolites employs a series of stimulated echo pulse sequences (90-TE/2-90-t.sub.1 -90-TE/2). The value of period t. sub.1 is different for each of the pulse sequences in the series, and the NMR signals produced by the series of pulse sequences are acquired and digitized to form a two-dimensional data array. A two- dimensional Fourier transformation is performed on this data array to produce an array of data that is employed to generate a contour plot.