NEW MATERIAL:A compound of formula I (n is 1-5; m and m' are each 0-2; excepting that n is 2 and m and m' are each zero). EXAMPLE:1alpha,3beta-Dihydroxy-20(S)-(4-hydroxy-4-methylpentyloxy)-9,10- secopregna-5,7,10(19)-triene. USE:Having strong differentiation-inducing ability for tumor cells, thus useful as an anti-neoplastic agent. PREPARATION:For example, using as starting material a 1alpha,3beta-bis(tert- butyldimethylsilyloxy)-pregna-5,7-diene-20(S)-ol of formula II (R is tert- butyldimethylsilyl), the compound of formula III described in the example can be obtained through the routes shown in the reaction formulas.
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