DRUG SUPPRESSING SECRETION OF ACID IN STOMACH AND PROTECTING STOMACH AND INTESTINES

摘要

PURPOSE: To prepare the subject medicine comprising a thienoimidazole derivative or its physiologically acceptable salt as an active ingredient. CONSTITUTION: This medicine comprises a compound of formula I A is formulae II, III (R1 and R2 are each H, a halogen, CN, NO2 , an alkyl, a hydroxyalkyl, an alkoxy, formula IV, etc.), etc.; T is S, SO or SO2 ; R3 is H, an alkanoyl, an alkylcarbamoyl, etc.; R4 and R5 are each H or an alkyl; R6 , R8 and R9 are each H, a halogen, an alkyl, an alkoxy, formula V, etc.; R7 is formula V; (f) is 1-10; (g) is 1 to [(2f)+1]; (x) is 0 or 1} or its physiologically acceptable salt as an active ingredient. 2-[4-(2,2,3,3,4,4,4-Heptafluorobutyloxy)-2-picolylsulfinyl]-1 H-thieno[3,4-d]imidazole, etc., are exemplified as the compound of formula I. The medicine is used for treating inflammatory gastroenteropathy, gastric ulcer, diarrhea, etc.