首页> 外国专利> LOW-MOLECULAR WEIGHT SYNTHESIS CARRIER SPECIFIC TO SUGAR ACCEPTOR, CONJUGATE BODY CONTAINING SAME, AND PREPARATION OF SAID CONJUGATE BODY

LOW-MOLECULAR WEIGHT SYNTHESIS CARRIER SPECIFIC TO SUGAR ACCEPTOR, CONJUGATE BODY CONTAINING SAME, AND PREPARATION OF SAID CONJUGATE BODY

机译:糖受体特异的低分子量合成载体,包含相同分子的结合体,以及所述结合体的制备

摘要

The subject of the present invention is a synthetic vector consisting of a chemical compound of low molecular weight, in particular lower than 5,000, which has an affinity for the cells exhibiting at their plasmic membrane receptors recognising specifically the sugar residues consisting of glycoside of saccharide rings, characterised in that it has a basic chemical structure to which are attached a number of glycoside of saccharide rings spaced so that each site for recognising these sugar residues of the receptor is capable of being occupied. A further subject of the present invention is the use of these vectors as an imaging agent or conjugates of this type of vector with a medication chosen especially from antitumour, antiviral and antiparasitic substances, and processes for the preparation of the said vectors.
机译:本发明的主题是由低分子量,特别是低于5,000的化合物组成的合成载体,该化合物对在其质膜受体上表现出的细胞具有亲和力,所述细胞特异性地识别由糖环的糖苷组成的糖残基。 ,其特征在于其具有基本的化学结构,在该化学结构上连接有间隔开的多个糖环的糖苷,使得识别受体的这些糖残基的每个位点都能够被占据。本发明的另一个主题是这些载体作为显像剂或这种类型的载体与特别选自抗肿瘤,抗病毒和抗寄生虫物质的药物的缀合物的用途,以及制备所述载体的方法。

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