certain glycolipids and specific catchere for these for use by profylaxe or therapy of diabetesand / or related complications, and the use of such glycolipids for detection of oe cell antibodies (ica) in an individual and the use of such catchere for detection of langerhans - oe cells in pancreatic preparations

摘要

Methods for the treatment of prediabetes or diabetes in an individual comprise administering to the individual a therapeutically active agent comprising a glycolipid having a galactose-3-O-sulfate moiety capable of binding to islet cell antibodies. Methods of detecting or quantifying islet cell antibodies in a sample, methods for the detection of Langerhans islet cells, methods for monitoring the development of prediabetes, diabetes or symptoms thereof in an individual and methods for prophylactic treatment against the development of prediabetes or diabetes also involve the use of a glycolipid having a galactose-3-O-sulfate moiety.