PROCESS FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE, L-ALPHA-GLYCERYLPHOSPHORYLETHANOLAMINE FROM CRUDE AND/OR DEOLEATED LECITHINS

摘要

An economical and industrially applicable process for the preparation of L- alpha -glycerylphosphorylcholine and L- alpha -glycerylphosphorylethanolamine from soy and/or crude egg lecithin, is described. The process of the invention comprises the alcoholysis of the crude and deoleated lecithins, the subsequent formation of insoluble complexes of the mixture of glycerylphosphorylcholine and glycerylphosphorylethanolamine with zinc chlorides or bromides, the de-complexation with organic bases such as pyridine, collidine, lutidine and the like and the final elution on ion-exchange resins.