STABLE SOLVENT ADDUCTS OF Z-1-(P-ב-DIMETHYLAMINOETHOXYPHENL) -1-(P-HYDROXYPHENYL)-2-PHENYL-BUT 1-ENE. PROCESS FOR THEIR PREPARATIO

摘要

Novel stereochemically pure and stable adducts of Z-1-(p- beta -dimethylaminoethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenyl- but-1-ene and certain solvents which, by virtue of their pronounced antioestrogenic activities, can be employed in the therapeutic treatment of benign breast disorders and hormone-dependent mammary tumours, in particular by percutaneous administration.