(4-HYDROXY-5,6-BIS(ALKOXYCARBONYL OR LACTONE)-7- DIALKOXYPHENYL)BENZO(6)THIOPHENE, QUINOLINE AND CARBAZOLE DERIVATIVES USEFUL AS HYPOLIPIDEMIC AGENTS

摘要

Biphenyl derivative of the formula: CHEM wherein R1 is hydrogen atom or a lower alkoxycarbonyl group and R2 is a lower alkoxycarbonyl group, or R1 and R2 are combined together to form a group of the formula: CHEM each of R3 and R4 is a lower alkoxy group; and Ring A is a substituted or unsubstituted sulfur-containing or nitrogen-containing heterocyclic ring, and a pharmaceutically acceptable salt thereof are disclosed. Said biphenyl derivative (I) and its salt have excellent hypolipidemic activity and are useful for treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.