SOLUBLE CYTOPLASMIC DOMAIN OF HUMAN CD2 RECEPTOR

摘要

This invention pertains to soluble peptides and DNA encoding the peptides that correspond to the cytoplasmic domain of human CD2 glycoprotein or portion thereof which is necessary for transduction of a CD2-mediated T lymphocyte activation signal into a cell. The invention also pertains to cells transformed to express a CD2 surface receptor, and to methods for screening substances which stimulate or block CD2 receptor function.