PREPARATION OF ?99m TC RADIOPHARMACEUTICALS

摘要

PCT No. PCT/AU84/00268 Sec. 371 Date Aug. 23, 1985 Sec. 102(e) Date Aug. 23, 1985 PCT Filed Dec. 21, 1984 PCT Pub. No. WO85/03063 PCT Pub. Date Jul. 18, 1985.Compounds of the formula I: R+[99mTcNX4]-I wherein R+ represents a cation and X represents a halo group, are prepared by reaction with an azide compound in the presence of a hydrohalic acid. The compounds are useful in production of 99mTc-labelled radio- pharmaceuticals by reaction with ligands and monoclonal antibodies or antibody fractions.