5- 2 - 2-AMINO-2-OXOETHYL METHYLAMINO ETHYL -2,3-DIHYDRO-3-HYDROXY-2- (4-METHOXYPHENYL) -1,5 (5H) -BENZOTHIAZEPINE-4 DERIVATIVES -ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.

摘要

Compounds, in the form of pure diastereomers or their mixtures, corresponding to the general formula (I) BR/ (CF DRAWING IN BOPI) BR/ BR/ in which R1 represents a hydrogen atom or a group C2-C4 alkanoyl, R2 represents a hydrogen atom or a C1-C4 alkyl group, n represents a number from 0 to 3, and R3 represents either a phenyl group carrying from 1 to 3 substituents chosen from atoms of halogen and trifluoromethyl, methyl, alkoxy or C1-C4 alkylthio, nitro, carbamoyl, acetamido, methanesulfonamido, methoxy carbonyl or phenylcarbonyl, or an aromatic heterocyclic group such as a pyridinyl or imidazolyl group BR/ Application in therapy.