Process for in vitro prenatal screening of foetal trisomy 21 in a biological sample capable of containing hCG and set for its implementation

摘要

The invention relates to a process for in vitro prenatal screening of trisomy 21 in a biological sample capable of containing hCG, characterised in that it comprises: - assaying the free beta hCG between the 14th and 15th amenorrhea; - assaying the total beta-hCG in the same sample; - comparing the free beta-hCG/total beta-hCG ratio to a threshold value corresponding to the free beta-hCG/normal total beta-hCG ratio, which value is measured during the same week. The invention also relates to the set or kit for implementing the process.