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Conjugated polyene sterol derivatives as membrane probes
Conjugated polyene sterol derivatives as membrane probes
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机译:共轭多烯固醇衍生物作为膜探针
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摘要
The present invention relates to the synthesis of conjugated polyene sterol derivatives, the compounds obtained and to their use as fluorescent probes for cellular membranes. The fluorescent probes of the present invention resemble cholesterol both structurally and in amphipathic nature. The probes of the present invention have potential for use in determining cholesterol levels and cholesterol properties and cell membrane properties and can be applied to clinical assays and diagnoses involving cholesterol.
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