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Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient

机译:制备dried干粉和以dried干粉为有效成分的降血脂,降糖,降压和降压制剂的生产方法

摘要

Disclosed is a process for the production of dried earthworm powder which comprises the steps of leaving a species of living earthworms in fresh water or a slightly acidic aqueous solution until the alimentary canal thereof is freed of soil, wet-grinding the living earthworms, and freeze-drying and then vacuum-drying the resulting suspension under a vacuum of 10 mmHg or below for 10 to 100 hours while raising the temperature stepwise from -60 C. to 80 C. This dried earthworm powder may be combined with pharmaceutically acceptable carriers to form pharmaceutical compositions which are useful for the treatment or prevention of hyperlipemia, diabetes, hypertension and hypotension in human beings.
机译:公开了一种生产干燥的powder粉的方法,该方法包括以下步骤:将一种活的earth种留在淡水或微酸性水溶液中,直到其消化道中没有土壤,然后湿磨该活的worm并冷冻。干燥,然后在10mmHg或以下的真空下真空干燥所得悬浮液10至100小时,同时将温度从-60℃逐步升高至80℃。该干燥的powder粉可与药学上可接受的载体混合以形成可用于治疗或预防人类高脂血症,糖尿病,高血压和低血压的药物组合物。

著录项

  • 公开/公告号US5024844A

    专利类型

  • 公开/公告日1991-06-18

    原文格式PDF

  • 申请/专利权人 EIMEI COMPANY LTD.;

    申请/专利号US19880228672

  • 发明设计人 YOICHI ISHII;HISASHI MIHARA;

    申请日1988-08-05

  • 分类号A61K35/56;

  • 国家 US

  • 入库时间 2022-08-22 05:46:22

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